Many
reputed scientists and medical researchers in India have expressed fear
that the new regulations on the use of animals for research work will
pose a major setback to the emerging areas of biotechnology and
biomedicine in the country. The new rules, notified recently, aim at
reducing cruelty to animals. Scientists and researchers, protesting
against them, say the move would put a full stop to all biomedical
research in India.
In the words of Dr. Ramlinga-swami, "Much of today’s
knowledge of the functioning of the human body and mind is derived from
animal experiments. The proposed rules work against facilitating science
and scientific research. All over the world, it is realised that
research and development holds the key to competitiveness and economic
growth."
As an example, consider the case of the dog that
helped heart surgeons develop and perfect artificial valves for
replacement in the human heart. Damage to the aortic valve—the valve in
the main artery from the heart to other organs in the body—is one of the
deadliest heart ailments. Researchers felt that a plastic or metal valve
made of material accepted by the human body, might be useful to bypass
the damaged valve. The idea was mechanically sound, but researchers
could not risk using an untested theory on human beings. So surgeons
removed a section of a dog’s aorta and inserted the world’s first
experimental valve. The dog lived for three years thereafter.
Further research and experiments on artificial valves
on dogs resulted in perfecting the valves as well as the procedure.
Today, these valves are made in India and thousands of people are alive
and working because many animals laid down their lives during the
research. Many people who had broken their bones are now walking with
metal rods in their bodies. Dogs again were responsible for this
successful research in stainless steel body implants. Also those
suffering from various eye and ear disorders are alive today, because in
attacking these ailments researchers experimented with monkeys and
chimpanzees, whose body make-up is most similar to ours.
White rats or guinea pigs are also commonly used in
medical research. Rats were used to study the effect of saccharine and
laxatives in humans. Toxicologists contend that a chemical that causes
cancer in rats or other animals is likely to do the same in humans.
Vitamin requirements, too, are usually determined by
experiments using rats, chicks, dogs, and guinea pigs in which the
increase in the animals’ body weight is related to the amounts of
vitamins in their diets. Dissection of frogs is carried out in schools
and colleges by students who study biology with a view to join medical
college. The aim is to get the students used to the sight of blood and
tissues as they advance in their studies and before they try their
scalpel on a human patient. The use of animals has not been limited to
medical research alone.
In the Draize test, developed in the 1940s, a
substance is dropped into a rabbit’s eyes to determine eye damage and
rate of recovery. Rabbits are used because their eyes produce no tears;
thus blinking will not wash away an irritant. Guinea pigs, too, were
used for testing after shave lotions in a most atrocious manner.
While animal tests measure only the harmful effects
of ingredients in cosmetics, they provide absolutely little or no
information on the effective treatment of injuries that may result to
human beings from the use of that product. According to the new rules,
all experiments on animals would need clearance from a central
committee. In addition to screening the need for the test, the committee
would also ensure that animals were treated with proper care and in a
humane manner. In response, Dr. N. K. Ganguli, Director General, Indian
Council of Medical Research – says, "Any one agency cannot handle it. By
the time, one gets a clearance from the committee, the need for the
experiment may be over." Dr. S. Basu, Director of the National Institute
of Immunology adds: "It is totally impractical; even a routine project
takes a very long time to be cleared. How will this committee clear so
many projects?" Researchers demand that there should be
institution-based committees and not a central committee. In fact, many
institutions where experiments are conducted on animals do have such
committees. These committees have lawyers, social scientists and medical
researchers as their members. What is necessary is to ensure that all
institutions have such committees. If scientists and doctors want to
defeat the killer diseases that still confront the human race—AIDS,
Alzheimer’s, cancer, heart disease and many others, animal experiments
are necessary to some extent.